BIOL 373 - Molecular Diagnostics

3 Credits
This course introduces students to the principles, methodologies, and applications of molecular diagnostics in the context of modern healthcare. It explores the foundation and advancements in molecular biology techniques and their critical role in diagnosing genetic disorders, infectious diseases, and cancer, among other conditions. Students will explore the theory behind techniques such as polymerase chain reaction (PCR), gel electrophoresis, DNA sequencing, and microarray analysis and understand their application in clinical diagnostics. The course emphasizes the clinical relevance of molecular diagnostics, covering topics such as assay development, validation, and the interpretation of results for patient management. Students will also learn about the regulatory environment affecting diagnostic testing, quality control measures, and the ethical considerations surrounding genetic testing.

Grade Note(s): All BIOL prefixed courses required for the BS Biological Sciences degree program require a C or better grade for successful completion.
Prerequisite(s): BIOL 354 and BIOL 354L
Corequisite(s): BIOL 373L
Course Learning Outcomes:
1. Evaluate assay protocols and diagnostic procedures.
2. Evaluate the ethical considerations and challenges associated with genetic testing and personalized medicine.
3. Analyze gel electrophoresis results.
4. Analyze the significance of assay validation, quality control, and regulatory standards in molecular diagnostics.
5. Apply advanced molecular biology techniques to diagnose and study diseases.
6. Describe the principles and methodologies of key molecular diagnostic techniques.
7. Explain the application of molecular diagnostics in the detection and management of diseases.