BIOL 336 - Genetics

4 Credits
This course presents an introduction to both classical and molecular genetics. Classic genetic concepts covered include Mendelian and Non-Mendelian patterns of inheritance, as well as linkage and chromosome mapping in eukaryotes and bacteria and bacteriophages. Molecular genetics topics include DNA structure, replication, mutation, and DNA repair; regulation of gene expression in both prokaryotes and eukaryotes; recombination and transposition at the molecular level. Genetic technologies including functional genomics, proteomics, bioinformatics, recombinant DNA, and biotechnology will be introduced and reinforced. Course content will facilitate student understanding of genetic analysis of individuals and populations. Special topics covered will include medical genetics and cancer and developmental genetics.

Grade Note(s): All BIOL prefixed courses required for the BS Biological Sciences degree program require a C or better grade for successful completion.
All BIOL prefixed courses taken as requirements in the Nursing programs require a C or better grade for successful completion.
Prerequisite(s): BIOL 211, BIOL 211L and MATH 150
Course Learning Outcomes:
1. Relate the structure and function of the DNA molecule to its functional role in encoding genetic material.
2. Extend the principles of inheritance as formulated by Mendel to multiple allelism, lethal alleles, gene interactions, and sex-linked transmission.
3. Apply the Hardy-Weinberg Law in analyzing population genetics for gene frequency, sex linkage, equilibrium, and heterozygote frequency.
4. Classify mutations in DNA and understand their direct effect on gene expression, inherited diseases, and cancer.
5. Explain how gene structure and expression impacts organism development.
6. Explain the relationship between genetic, physical, and cytogenetic maps.
7. Describe how information generated from genomic and proteomic bioinformatic analysis can be used to discover practical knowledge about gene expression, relationships between species, and human disease.
8. Describe how various applications of recombinant DNA technology are utilized in genetic engineering and biotechnology.